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A brinzolamide (BRN) formulation incorporating two different types of PLGA nanoparticles was injected into the subconjunctival Room of normotensive Albino rabbits. The reduction of IOP in both BRN-loaded PLGA nanoparticle preparations was better than topical BRN suspension by itself for as much as 10d[24]. Other subconjunctival nanoparticle deliver